Ortopedia e Traumatologia - Sizínio 4ed - Ebook download as PDF File .pdf) or read book online. ortopedia e traumatologia-Sizínio 4ed. ortopedia e traumatologia - sizinio hebert 2a medical-site.info - Ebook download as PDF File .pdf) or read book online. (Télécharger) Mon carnet de santé psy pdf de Sophie Marinopoulos .. Ortopedia. Consulta Rápida. Exames e medical-site.info baixar Sizinio H. Hebert .
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The time use of DVT prophylaxis with institutional protocol is 10 to 35 days, depending on each specific case for the high-risk groups of developing the disease. Most of the patients are discharged from the hospital and continues to take the medication at home, which explains the average time that the antithrombotic used was greater than the average hospital stay Brasil, It is important to note that the average of There are exceptions in the case of 7 patients who remained in the hospital for orthopedic complications and to prevent the occurrence of DVT, had more than 35 days of low molecular weight heparin, which is not recommended Brasil, An international reference on pharmaceuticals, says that for prophylaxis, the ideal is to achieve 40 mg of low molecular weight heparin, 1 time a day for 6 to 11 days, no more than14 days.
Taking into consideration the information of Drugs Drug Information Online, and the institutional protocol itself, it is observed that some patients were exposed to prolonged therapy, even though all were within the recommended dosages, i. Of the 20 patients, 3 of them were undergoing DVT treatment in a longer delayed post-operative.
The institutional protocol for DVT treatment, which consists of using oral anticoagulants, in the case of the place of study, warfarin starting with 5 mg day and, subsequently, adjusting as INR of the patient for 3 months or more and can combine low weight heparin until 5 days was followed correctly in relation to warfarin.
On the other hand, 1 patient had association with low molecular weight heparin, at the dosage indicated, but for an extended period 29 days. In total 15 different types of ADRs were identified. According to the label of enoxaparin and warfarin in Drugs, most ADRs confirm this as possible to happen with continued therapy, however, vomiting, oral bleeding, epistaxis, dark urine, melena and changes of the TAP are not reported.
None of the labels indicated melena as an ADR, which suggests that there may have been an incongruity in control of laboratory tests and proper adjustment of dosages in two cases found in the study. One of them came in a patient who had prophylaxis with enoxaparin and the other with patient who was receiving DVT treatment with warfarin Diogo, When applying the Naranjo algorithm for determining the probability of causation, failed to qualify any ADR as defined.
Most of the ADRs were classified as possible. It is important to remember that in Brazil it is recommended that after the completion of the questions and determining if, the reaction has definite or probable causality; such a reaction should have priority for immediate action as the ban of one or more lots, the dissemination of warnings and sending notifications to the National Health Surveillance Agency.
That reaction defined as possible or doubtful, too, will need stimulus actions to obtain greater number of notifications, as disclosure, alerts in order to strengthen the hypothesis Capucho, The total of ADRs evaluated was Of these, Regarding the severity it is observed that It is worth mentioning that there are criteria of predictability of the ADRs, so that some conditions are controlled.
Dosage, frequency and administration appropriate to age, weight and condition of the patient; therapeutic monitoring and other laboratory tests and interaction with other administered drugs. Based on these parameters, all the ADRs identified in the study were considered predictable.
The consequences of the use of medicines and clinical and economic impacts directly influence quality of care and safety of who uses them. Adverse Drug Reactions are a response to a drug that is harmful, unintentional and which occurs at doses used in humans. By occurring this way, it is difficult to intervene before their occurrence, however, the patient monitoring by the health care team is important for them to act minimizing the damage caused by the ADR.
The under reporting is still a very common problem, which hinders the correct intervention. The need for continuing education in noted for health professionals, with the objective of guidance on the identification of ADR and its proper notification Abrhiem, As mentioned above, one of the main methods used for pharmacovigilance for identification of adverse reaction is suspected, reporting made by health professionals.
The spontaneous reporting system can generate signs of relationship between the use of the medicine and the development of ADR and its success or failure depends on the active participation of the notifiers.
Thus, the reporting of ADR is crucial to accurate description of the event, whereas including the clinical terms. Considering that drug therapy is widely used as a treatment modality for customers with several health changes, the identification of the adverse event related to medicines gain prominence in search of the management of safety and quality in healthcare.
The attitude of constant vigilance to identify faults that occur becomes a concern of professionals involved in the care management system in healthcare, the users and institutions to increasingly minimize possible damage to the patient and reduce the costs with complications of hospitalization.
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