No part of this book may be reproduced or transmitted in any form or by Rev. ed. of: Biochemistry / Pamela C. Champe, Richard A. Harvey, Denise R. Ferrier. No part of this book may be reproduced or transmitted in any form or by any ( Lippincott's illustrated reviews) Rev. ed. of: Biochemistry / Richard A. Harvey. the captain standing on the bridge, could press a button and-presto! to live with ' day-tight compartments' as the most Textbook of Biochemistry - For Medical.
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The Dalmatian dog has a genetic defect in uric acid uptake by the liver and kidneys , resulting in decreased conversion to allantoin, so this breed excretes uric acid, and not allantoin, in the urine. In birds and reptiles , and in some desert dwelling mammals such as the kangaroo rat , uric acid also is the end-product of purine metabolism, but it is excreted in feces as a dry mass.
This involves a complex metabolic pathway that is energetically costly in comparison to processing of other nitrogenous wastes such as urea from the urea cycle or ammonia , but has the advantages of reducing water loss and preventing dehydration. Platynereis dumerilii , a marine polychaete worm, uses uric acid as a sexual pheromone. The female of the species releases uric acid into the water during mating , to induce males to release sperm. Likewise, uric acid concentrations in urine above and below normal are known as hyperuricosuria and hypouricosuria.
Uric acid levels in saliva may be associated with blood uric acid levels.
High intake of dietary purine , high-fructose corn syrup , and table sugar can increase levels of uric acid. Consumption of some types of purine-rich foods, particularly meat and seafood, increases gout risk.
Today, inflammation during attacks is more commonly treated with NSAIDs , colchicine, or corticosteroids , and urate levels are managed with allopurinol.
These uric acid stones are radiolucent and so do not appear on an abdominal plain X-ray. Low dietary zinc intakes cause lower uric acid levels.
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